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CLOSED · 20:55 ET
Market ClerkRecap
Wed Oct 21 · markets closed2 signals today78 insider buys this week · $240.8MCIRO short report next: Oct 31The week ahead

SYRE

Spyre Therapeutics, Inc.
NASDAQ · HEALTH CARE · PHARMACEUTICAL PREPARATIONS
92.95
+1.55 +1.70%
USD · close Oct 21

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MKT CAP $8.2BP/E —DIV YIELD —FCF YIELD —REV TTM —NET INCOME −$178.9MNET CASH —52W 22.18 – 108.92NEXT EARNINGS Nov 3 EST.SEC XBRL · TTM TO Invalid Date

One year, everything drawn on

252 SESSIONS · DAILY CLOSES
116824915Oct 1 · See Remarks sell $243KOct 1 · See Remarks sell $195KOct 1 · See Remarks sell $660KOct 1 · See Remarks sell $1.5MOct 1 · See Remarks sell $36KOct 1 · Chief Financial Officer sell $21KOct 1 · Chief Financial Officer sell $285KOct 1 · Chief Financial Officer sell $193KOct 1 · Chief Financial Officer sell $135KOct 1 · Chief Financial Officer sell $53KSep 30 · Chief Financial Officer sell $1.6MSep 2 · See Remarks sell $36KSep 2 · Chief Financial Officer sell $1.6MSep 1 · Chief Executive Officer sell $36KSep 1 · Chief Executive Officer sell $326KSep 1 · Chief Executive Officer sell $732KSep 1 · Chief Executive Officer sell $216KSep 1 · See Remarks sell $36KSep 1 · See Remarks sell $547KSep 1 · See Remarks sell $1.4MSep 1 · See Remarks sell $419KSep 1 · Chief Financial Officer sell $18KSep 1 · Chief Financial Officer sell $177KSep 1 · Chief Financial Officer sell $382KSep 1 · Chief Financial Officer sell $78KAug 4 · 10-Q filed (Q2 2026)Aug 4 · 10-Q filed (Q1 2026)Feb 19 · 10-K filed (FY 2025)Feb 19 · 10-K filed (Q4 2025)Nov 4 · 10-Q filed (Q3 2025)Aug 4 · 10-Q filed (Q2 2025)Aug 4 · 10-Q filed (Q1 2025)Feb 19 · 10-K filed (FY 2024)Feb 19 · 10-K filed (Q4 2024)Nov 4 · 10-Q filed (Q3 2024)Nov 4 · 10-Q filed (Q2 2024)Nov 4 · 10-Q filed (Q1 2024)Feb 19 · 10-K filed (FY 2023)Feb 19 · 10-K filed (Q4 2023)OCT 2025JAN 2026APRJUL
Insider buyInsider sellCongress buy, above the lineCongress sell, below10-K / 10-Q filedHOVER A MARKER FOR THE FILING
THE WORK ORDER · 2026-10-21
Insiders (90d): $11M net selling
Shorts (latest report): 11.9M short · +105K last period
Every line of the math
37FLAG

Congress is trading it

No STOCK Act disclosure names SYRE.

Insider activity

ALL 25
DateInsiderTypeValue
Oct 1See RemarksSell$243K
Oct 1See RemarksSell$195K
Oct 1See RemarksSell$660K
Oct 1See RemarksSell$1.5M
Oct 1See RemarksSell$36K
Oct 1Chief Financial OfficerSell$21K
Watch SYRE. Know when insiders buy.
One email the day a filing lands. Free.