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| Traded | Filed | Insider | Type | Shares | Price | Value |
|---|---|---|---|---|---|---|
| Oct 20 | Oct 20 | Quinlan Paul T · General Counsel | Sell | 3,000 | $79.49 | $238K |
| Oct 20 | Oct 20 | Quinlan Paul T · General Counsel | Sell | 4,100 | $78.79 | $323K |
| Oct 20 | Oct 20 | Quinlan Paul T · General Counsel | Sell | 1,000 | $77.20 | $77K |
| Oct 20 | Oct 20 | Quinlan Paul T · General Counsel | Sell | 500 | $76.12 | $38K |
| Oct 20 | Oct 20 | Quinlan Paul T · General Counsel | Sell | 400 | $74.90 | $30K |
| Oct 15 | Oct 15 | Goncalves Joana · Chief Medical Officer | Sell | 200 | $77.71 | $16K |
| Oct 15 | Oct 15 | Goncalves Joana · Chief Medical Officer | Sell | 700 | $76.67 | $54K |
| Oct 15 | Oct 15 | Goncalves Joana · Chief Medical Officer | Sell | 1,400 | $75.48 | $106K |
| Oct 15 | Oct 15 | Goncalves Joana · Chief Medical Officer | Sell | 1,847 | $74.69 | $138K |
| Oct 15 | Oct 15 | Goncalves Joana · Chief Medical Officer | Sell | 2,853 | $73.89 | $211K |
| Oct 12 | Oct 13 | Agarwal Arjun · Senior Vice President, Finance | Sell | 200 | $82.83 | $17K |
| Oct 12 | Oct 13 | Agarwal Arjun · Senior Vice President, Finance | Sell | 1,958 | $81.86 | $160K |
| Oct 12 | Oct 13 | Agarwal Arjun · Senior Vice President, Finance | Sell | 2,100 | $80.76 | $170K |
| Oct 12 | Oct 13 | Agarwal Arjun · Senior Vice President, Finance | Sell | 5,741 | $80.03 | $459K |
| Oct 1 | Oct 2 | Klein Lawrence Otto · Chief Executive Officer | Sell | 200 | $84.78 | $17K |
| Oct 1 | Oct 2 | Klein Lawrence Otto · Chief Executive Officer | Sell | 8,554 | $84.03 | $719K |
| Oct 1 | Oct 2 | Klein Lawrence Otto · Chief Executive Officer | Sell | 16,246 | $83.40 | $1.4M |
| Sep 21 | Sep 21 | Quinlan Paul T · General Counsel | Sell | 2,667 | $95.31 | $254K |
| Sep 21 | Sep 21 | Quinlan Paul T · General Counsel | Sell | 601 | $94.44 | $57K |
| Sep 21 | Sep 21 | Quinlan Paul T · General Counsel | Sell | 3,832 | $93.32 | $358K |
| Sep 21 | Sep 21 | Quinlan Paul T · General Counsel | Sell | 2,900 | $92.37 | $268K |
| Sep 21 | Sep 21 | Agarwal Arjun · Senior Vice President, Finance | Sell | 533 | $95.75 | $51K |
| Sep 15 | Sep 15 | Quinlan Paul T · General Counsel | Sell | 1,039 | $95.71 | $99K |
| Sep 15 | Sep 15 | Sandler Laura Lee · Chief Operating Officer | Sell | 906 | $95.71 | $87K |
| Sep 15 | Sep 15 | Klein Lawrence Otto · Chief Executive Officer | Sell | 2,452 | $95.71 | $235K |
| Sep 15 | Sep 15 | Goncalves Joana · Chief Medical Officer | Sell | 947 | $95.71 | $91K |
| Sep 15 | Sep 15 | Goncalves Joana · Chief Medical Officer | Sell | 100 | $94.22 | $9K |
| Sep 15 | Sep 15 | Goncalves Joana · Chief Medical Officer | Sell | 1,366 | $92.99 | $127K |
| Sep 15 | Sep 15 | Goncalves Joana · Chief Medical Officer | Sell | 3,150 | $92.03 | $290K |
| Sep 15 | Sep 15 | Goncalves Joana · Chief Medical Officer | Sell | 2,384 | $91.10 | $217K |
| Sep 15 | Sep 15 | Agarwal Arjun · Senior Vice President, Finance | Sell | 560 | $95.71 | $54K |
| Sep 11 | Sep 15 | Agarwal Arjun · Senior Vice President, Finance | Sell | 200 | $94.02 | $19K |
| Sep 11 | Sep 15 | Agarwal Arjun · Senior Vice President, Finance | Sell | 2,208 | $93.26 | $206K |
| Sep 11 | Sep 15 | Agarwal Arjun · Senior Vice President, Finance | Sell | 4,051 | $92.41 | $374K |
| Sep 11 | Sep 15 | Agarwal Arjun · Senior Vice President, Finance | Sell | 3,000 | $91.11 | $273K |
| Sep 1 | Sep 1 | Sandler Laura Lee · Chief Operating Officer | Sell | 4,000 | $92.01 | $368K |
| Sep 1 | Sep 1 | Sandler Laura Lee · Chief Operating Officer | Sell | 1,000 | $91.05 | $91K |
| Sep 1 | Sep 1 | Klein Lawrence Otto · Chief Executive Officer | Sell | 4,800 | $92.44 | $444K |
| Sep 1 | Sep 1 | Klein Lawrence Otto · Chief Executive Officer | Sell | 63,596 | $91.90 | $5.8M |
| Sep 1 | Sep 1 | Klein Lawrence Otto · Chief Executive Officer | Sell | 6,604 | $90.79 | $600K |
Source: SEC EDGAR Form 4 filings, pulled nightly; open-market purchases and sales only, no option exercises or grants. The tracker, all tickers.